Category: The Breast

The Breast is an international, multidisciplinary journal for researchers and clinicians, which focuses on translational and clinical research for the advancement of breast cancer prevention, diagnosis and treatment of all stages. The Editors welcome the submission of original research articles, systematic reviews, and viewpoint/commentary and debate articles, and correspondence on all areas of pre-malignant and malignant breast disease, including:

• Epidemiology and prevention
• Translational research, encompassing the use of new technologies, molecular biology, genetics and pathology
• Screening, early diagnosis, follow-up and response assessment: use of imaging, nuclear medicine and other technologies
• Medical oncology
• Radiation oncology
• Breast surgery
• Psycho-oncology
• Quality of life
• Survivorship
• Supportive care
• Palliative and end-of-life care
• Advocacy
• Breast Nursing
• Breast Units management and organization of breast care, including health economics

Oncology / The Breast

Agreement on risk assessment and chemotherapy recommendations among breast cancer specialists: A survey within the MINDACT cohort

Breast, The, Volume 71, 2023 Oct, Pages 143-149 | Lopes Cardozo, Josephine M.N.; Veira, Sherylene E.; Ait Hassou, Laila;…
AbstractPurposeTailored recommendation for adjuvant chemotherapy in breast cancer patients is of great importance. This survey assessed agreement among oncologists on risk assessment and chemotherapy recommendation, the impact of adding the 70-gen…

Oncology / The Breast

Individualising radiation therapy decisions in breast cancer patients based on tumour infiltrating lymphocytes and genomic biomarkers

Breast, The, Volume 71, 2023 Oct, Pages 13-21 | Machiels, Melanie; Oulkadi, Redouane; Tramm, Trine;…
AbstractRadiation therapy (RT) has long been fundamental for the curative treatment of breast cancer. While substantial progress has been made in the anatomical and technological precision of RT delivery, and some approaches to de-escalate or omit…

Oncology / The Breast

The role of CDK4/6 inhibitors in older and younger patients with breast cancer: A systematic review and meta-analysis

Breast, The, Volume 71, 2023 Oct, Pages 138-142 | Petrelli, Fausto; Dottorini, Lorenzo; Di Menna, Giandomenico;…
AbstractIntroductionCyclin-dependent kinase 4/6 (CDK4/6) inhibitors have an extremely important impact on the treatment of hormone-sensitive breast cancer (BC) and have radically changed the first-line treatment for metastatic disease with increas…

Oncology / The Breast

Differences between the efficacy of HER2(2+)/FISH-positive and HER2(3+) in breast cancer during dual-target neoadjuvant therapy

Breast, The, Volume 71, 2023 Oct, Pages 69-73 | Chen, Wei; Li, Fen-Xiang; Lu, Da-Lin;…
AbstractIntroductionThis study investigated the differences in efficacy between IHC(2+)/FISH-positive and IHC(3+) in HER2-positive breast cancer (BC) during neoadjuvant chemotherapy (NAC) combined with trastuzumab and pertuzumab. The research also…

Oncology / The Breast

Direct and indirect effects of COVID-19 on short-term mortality of breast cancer patients

Breast, The, Volume 71, 2023 Oct, Pages 60-62 | Di Cosimo, Serena; Ljevar, Silva; Trama, Annalisa;…
AbstractWe studied the COVID-19 impact in newly-diagnosed breast cancer (7,349 patients in 2019, and 5,563 in 2020). In 2020 there were two diagnostic drops: −37.2% (March–May), −15.8% (October–December). Early-stage at presentation (76.4% vs. 74….