Tagged: Obstetrics

Neurocognitive sequelae of antenatal corticosteroids in a late preterm rabbit model

Late-preterm birth (PTB) is associated with short-term respiratory and adaptive problems. Although antenatal corticosteroid (ACS) seems to reduce the respiratory burden, this may come at the cost of adverse neuropsychological outcomes later in life. This impact has not been investigated. Herein, we investigate what the short- and long-term neurodevelopmental effects are of a single course of betamethasone in simulated late PTB.

Sleep-disordered breathing in high-risk pregnancies is associated with elevated arterial stiffness and increased risk for preeclampsia

Impaired vascular function is a central feature of pathologic processes preceding the onset of preeclampsia. To this end, arterial stiffness, a composite indicator of vascular health and an important vascular biomarker, has been found to be increased throughout pregnancy in those destined to develop preeclampsia and at the time of preeclampsia diagnosis. While sleep-disordered breathing in pregnancy has been associated with increased risk for preeclampsia, it is unknown if sleep-disordered breathing is associated with elevated arterial stiffness in pregnancy.

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