Prediction of Heart Failure Events with the HeartLogic Algorithm: Real-World Validation

HeartLogic™ is an algorithm that uses ICD/CRT-D sensor data for the prediction of heart failure (HF) events. The algorithm integrates heart sounds, respiration, thoracic impedance, heart rate, and activity measures. When early changes suggestive of decompensation are identified alerts are sent remotely to healthcare providers. The algorithm was developed and validated in separate cohorts of CRT-D patients from the MultiSENSE study1. In the present study we sought to re-validate algorithm performance in an independent cohort, including ICD patients, by using a novel real-world data approach.